Bottle of Lies: The Inside Story of the Generic Drug Boom

书名:Bottle of Lies: The Inside Story of the Generic Drug Boom
豆瓣评分: 9.5


Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.


Katherine Eban, an investigative journalist, is a Fortune magazine contributor and Andrew Carnegie fellow. Her narrative, deeply reported articles on pharmaceutical counterfeiting, gun trafficking, and coercive interrogations by the CIA, have won international attention and numerous awards. She lectures frequently on the topic of pharmaceutical integrity. Bottle of Lies: The Inside Story of the Generic Drug Boom, which she worked on for five years and reported on four continents, is her second book. Educated at Brown University and Oxford, where she was a Rhodes Scholar, she lives in Brooklyn with her husband, two daughters and Newfoundland dog Romeo.


@ 米娅 “Classically good reason to be suspect of production coming from any country that doesn’t have competent regulatory authority.” @ yusen 好的质量控制来自于对过程关键环节的把控,以及事先没有通知的检查。而不是对成品的ad-hoc抽查。而全书讲述的FDA inspector在全世界各地工厂质检抽查的经历,为何就这么让人感到熟悉呢?尾声尤其值得一读。 @ Lububu 哇 精彩! @ 2s 这是不是FDA 是FBI简直 @ Ann 这本书给我感觉和bad blood很像,也是一个记者多方访谈追踪揭露制药厂的骗局,读下来触目惊心,一遍遍问这是真的吗?真的吗?怎么会这样?FDA完全不可信了?简单结论就是千万不要再吃generic drugs了! @ 抵挡太平洋 FH 之前一个报道说公共卫生问题是最常被block的三个新闻话题之一 对比着中文版本的页数看 这下知道原因了? @ Nussknacker investigative journalism比侦探悬疑武侠都好读!本来是要坚定信心好好赚钱just so that I can pay whatever for the non generics,后面读到drug resistance那段觉得也无所谓了,?大家一起玩完。 @ 莺啼山客犹眠 比上次某一本不记得名字的制药科普写的好!(真是毫无意义的评价) @ Mark 做动物实验的时候,用左氧氟沙星,喂老鼠几天,吃药的老鼠跪了,问题是没吃药的对照组老鼠好好的…后来左氧氟沙星就再也不敢买国产的喂老鼠了,毕竟P3实验室费用挺高的,这钱真不敢省 @ GW_Parables 这本书写的只是冰山一角..翻完了..YD的仿制药至少还买个分子式抄抄..某国药厂是直接买成品药来倒推..高瓴资本/高毅冯柳/睿远成长价值参与的那些股票..韭菜们激动的整天叫唤医药漂亮50..实际占的这点便宜都会加倍向他们和他们的父辈索还的…医药行业背后大手不停stir up trouble 国采一刀切最后倒霉的还是患者。


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